KEI SPR Can provide
Investigation of steric/allosteric effects
Binding strength for molecular interactions – affinity constants
Discrimination between active and non-active molecules
Information regarding biocompatibility with coatings
Quantitative information – total concentration of biomolecules in solution
Specificity of the interaction
A qualitative tool for ligand screening
Complex assembly studies information
Determination of reaction kinetics
The ESPRIT is designed for high throughput SPR experiments. The automation allows reproducible measurements with the possibility to analyze up to 192 samples without user intervention. The double channel reference measurement can be used to correct for experimental errors and/or matrix effects. The autosampler is controlled by the liquid handling tool in the software. Samples are taken from the microwell plate and injected in the cuvette. The automatic control allows the user to run measurements continuously, unattended. The ESPRIT instrument is standard supplied with a normal cuvette, an electrochemical cuvette is optional.
The TWINGLE is designed for high quality, high accuracy measurements and is the economical choice for dual channel surface plasmon resonance measurements. The reference channel data can be used to correct for experimental errors and/or matrix effects. The TWINGLE is standard supplied with a normal cuvette, an electrochemical cuvette is optional.
The SPRINGLE is the entry-level single channel SPR instrument. It provides high performance SPR measurements at a convenient price. The SPRINGLE is ideal for fundamental research and development and is standard supplied with an electrochemical (ESPR) cuvette.
What makes us different?
The KEI SPR instruments have a flexible open cuvette system.
The cuvette has many advantages:
●Sample volume independent of applicatio
●Incubation time independent of sample volume
●Sample incubation for 1 minute, 1 hour, 1 day or even 1 week
●Only the needle tip is in contact point with the sample – no contamination
●Viscosity independent – no clogging
●Sample recovery possible without additional modules
●Easy access for manual additions and modifications
The normal cuvette is the appropriate choice for measuring the lowest affinity binding systems as well as the highest affinity binding systems and is standard supplied with ESPRIT and TWINGLE